Disease: Acidosis, Lactic
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WARS2 Q9UGM6 tryptophanyl tRNA synthetase 2, mitochondrial 5.1E-02 0.617 0.577
VARS2 Q5ST30 valyl-tRNA synthetase 2, mitochondrial 5.8E-17 0.666 0.577
UQCRFS1 P47985 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 0.19 0.558 0.654
UQCC2 Q9BRT2 ubiquinol-cytochrome c reductase complex assembly factor 2 1.9E-02 0.705 0.462
TYMP P19971 thymidine phosphorylase Enzyme 1.2E-04 0.495 0.769
TXNIP Q9H3M7 thioredoxin interacting protein 0.16 0.490 0.731
TTR P02766 transthyretin Transporter 0.52 0.423 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
SCO2 O43819 synthesis of cytochrome C oxidase 2 Enzyme 7.5E-07 0.479 0.846
RPS6KA3 P51812 ribosomal protein S6 kinase A3 Kinase 1.00 0.491 0.846
PTGS1 P23219 prostaglandin-endoperoxide synthase 1 Enzyme 6.2E-07 0.460 0.885
PTBP1 P26599 polypyrimidine tract binding protein 1 1.00 0.517 0.769
PLAT P00750 plasminogen activator, tissue type Enzyme 5.7E-05 0.445 0.885
NDUFS3 O75489 NADH:ubiquinone oxidoreductase core subunit S3 5.8E-04 0.581 0.769
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 Kinase 1.00 0.419 0.808
LRPPRC P42704 leucine rich pentatricopeptide repeat containing 2.3E-10 0.493 0.769
IL6 P05231 interleukin 6 0.32 0.248 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
HSPA5 P11021 heat shock protein family A (Hsp70) member 5 0.77 0.434 0.885
DNM1L O00429 dynamin 1 like Enzyme modulator 5.7E-04 0.475 0.808
COX8A P10176 cytochrome c oxidase subunit 8A Enzyme 0.12 0.400 0.846
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
COX1 P00395 cytochrome c oxidase subunit I Enzyme 0.441 0.885